Table II.
Frequent Arg mutations at AGC and AGT codons in V genes
V genes | Arg mutations at AGC | Arg mutations at AGT | AGC codons in V genesa | AGT codons in V genes | AGC+AGT CDR1 and CDR2 | AGC+AGT FR1 and FR2 |
% | % | % | % | % | % | |
VH | 41.7 | 16.7 | 3.7 | 2.0 | 10.8 | 1.8 |
Vκ | 38.9 | 33.3 | 3.0 | 6.1 | 17.9 | 1.9 |
This table refers to anti-chromatin antibodies in this study.
AGC and AGT codon usage among 52,926 mouse genomic codons is 1.6 and 0.92%, respectively (GenBank: http://www.kazusa.or.jp/codon/cgi-bin/showcodon.cgi?species=10092).