Table III.
Frequent use of AGC and AGT codons in antibody V genes
| V genes | AGC codon use | AGT codon use | ||
| All mouse V genesa | All human V genesb | All mouse V genes | All human V genes | |
| % | % | % | % | |
| VH | 3.1 | 3.4 | 1.67 | 2.2 |
| Vκ | 2.6 | 3.9 | 5.5 | 4.7 |
| Vλ | 2.4 | 3.4 | 2.4 | 2.4 |
This table shows V gene sequences taken directly from Ig BLAST (http://www.ncbi.nlm.nih.gov/igblast/). A majority of the Ig BLAST sequences were from the international ImMunoGeneTics information system (IMGT; http://www.imgt.org).
a
AGC and AGT codon usage among 52,926 mouse genomic codons is 1.6 and 0.92%, respectively (GenBank: http://www.kazusa.or.jp/codon/cgi-bin/showcodon.cgi?species=10092).
b
AGC and AGT codon usage among 40,662,582 human genomic codons is 1.95 and 1.21%, respectively (GenBank: http://www.kazusa.or.jp/codon/cgi-bin/showcodon.cgi?species=9606).