Figure 2.
Mut-p53 does not enhance MEF infection efficiency or possess a GOF activity in promoting MEF proliferation. (A) p53 KO, p53R172H, and WT MEFs were infected with three factors and GFP. The percentage of cells expressing GFP was measured 5 d after infection by flow cytometry. Noninfected MEFs were used as a negative control. A representative experiment out of two independent infections is shown. (B) Cumulative population doubling of uninfected WT p53, p53 KO, and p53R172H MEFs. A representative experiment out of two is shown.