Table 1. Genetic classification of Charcot–Marie–Tooth disease and related peripheral neuropathies.

CMT	Locus	Gene	Product	OMIM
CMT1A	17p11.2	PMP22	Peripheral myelin protein 22	118220
CMT1B	1q22	MPZ	Myelin protein zero	118200
CMT1C	16p13.1–p12.3	SIMPLE/LITAF	SIMPLE	601098
CMT1D	10q21.1–q22.1	EGR2	Early growth response protein 2	607678
CMT1E	17p11.2	PMP22	Peripheral myelin protein 22	118220
CMT1F	8p21	NEFL	Neurofilament triplet L protein	607684
CMT2A	1p36	MFN2	Mitofusin 2	118210
CMT2B	3q21	RAB7	Ras-related protein Rab-7	600882
CMT2B1	1q21.2	LMNA	Lamin A/C	605588
CMT2B2	19q13.3	Unknown	Unknown	605589
CMT2C	12q23–q24	Unknown	Unknown	606071
CMT2D	7p15	GARS	Glycyl-tRNA synthetase	601472
CMT2E/F1	8p21	NEFL	Neurofilament triplet L protein	607684
CMT2F	7q11–q21	HSPB1	Heat-shock protein B1	606595
CMT2G	12q12–q13	Unknown	Unknown	608591
CMT2H	8q21.3	Unknown	Unknown	607731
CMT2I	1q22	MPZ	Myelin protein zero	118200
CMT2J	1q22	MPZ	Myelin protein zero	118200
CMT2K	8q13–q21.1	GDAP1	Ganglioside-induced differentiation protein 1	214400
CMT2L	12q24	HSPB8	Heat shock protein B8	608673
CMT4A	8q13–q21.1	GDAP1	Ganglioside-induced differentiation protein 1	214400
CMT4B1	11q22	MTMR2	Myotubularin-related protein 2	601382
CMT4B2	11p15	SBF2/MTMR13	SET binding factor 2	604563
CMT4C	5q32	SH3TC2	SH3TC2	601596
CMT4D	8q24.3	NDRG1	NDRG1 protein	601455
CMT4E	10q21.1–q22.1	EGR2	Early growth response protein 2	607678
CMT4F	19q13.1–q13.2	PRX	Periaxin	145900
CMT4G	10q23.3	Unknown	Unknown	605285
CMT4H	12p11.21–q13.11	FGD4	FRABIN	609311
CMT4J	6q21	FIG4	FIG4	611228
DI-CMTA	10q24.1–q25.1	Unknown	Unknown	606483
DI-CMTB	19p12–13.2	DNM2	Dynamin 2	606482
DI-CMTC	1p35	YARS	Tyrosyl-tRNA synthetase	608323
DI-CMTD	1q22	MPZ	Myelin protein zero	607791
CMTX	Xq13.1	GJB1	Gap junction β-1 protein, connexin 32	302800