Skip to main content
. Author manuscript; available in PMC: 2010 Sep 29.
Published in final edited form as: J Immunol. 2009 Feb 1;182(3):1270–1277. doi: 10.4049/jimmunol.182.3.1270

Table II.

Normalized expression level of genes for chemokines and their receptorsa

Gene GenBank Probe Set LAM Malme-3M PASM
CX3CL1b,c U84487 823_at 2.69 2.21 0.69
CCL18b,c Y13710 32128_at 4.73 0.91 0.07
XCR1 NM_005283 221468_at 0.12 0.21 0.14
CCL24 NM_002991 221463_at 0.09 0.12 0.15
CCR10d NM_016602 220565_at 0.46 0.87 0.67
CCRL1 NM_016557 220351_at 0.54 0.29 0.59
CXCL14 NM_004887 218002_s_at 0.68 0.12 0.17
CXCR3 Z79783 217119_s_at 0.06 0.08 0.05
CXCR4c,d AJ224869 217028_at 11.44 0.43 0.08
CCL13 Z77651 216714_at 0.19 0.10 0.12
CCL2b,c S69738 216598_s_at 0.18 0.10 1.87
CXCL5 BG166705 215101_s_at 0.07 0.07 0.14
CXCL5b,c AK026546 214974_x_at 0.44 0.26 31.00
XCL2 NM_003175 214567_s_at 0.09 0.06 0.05
SCYA8 AI984980 214038_at 0.97 0.27 0.38
CXCR7d AI817041 212977_at 4.76 0.15 0.89
CXCR4 AF348491 211919_s_at 2.11 1.63 1.69
GPR30 U58828 211829_s_at 0.05 0.04 0.05
IL8b,c AF043337 211506_s_at 0.17 0.33 2.09
CXCR6 U73531 211469_s_at 0.23 0.31 0.29
CCRL2 AF015524 211434_s_at 0.31 0.11 0.06
CXCL11 AF002985 211122_s_at 0.16 0.14 0.29
CMKLR1 U79526 210659_at 0.95 0.52 0.56
CCL23 U58913 210549_s_at 0.14 0.10 0.09
CCL23 U58913 210548_at 0.21 0.19 0.15
CCL15 AF031587 210390_s_at 0.15 0.53 0.14
CXCL11 AF030514 210163_at 0.14 0.07 0.10
CCL11 D49372 210133_at 0.85 0.75 0.51
CCL19 U88321 210072_at 0.48 0.14 0.09
CCL18b,c AB000221 209924_at 4.47 1.26 0.54
CXCL2b,c M57731 209774_x_at 9.68 0.57 13.78
CXCL12b,c U19495 209687_at 8.82 0.15 0.76
CXCR4 L01639 209201_x_at 1.82 1.55 1.07
CCR4 NM_005508 208376_at 0.47 0.35 0.55
CCR3 NM_001837 208304_at 0.13 0.13 0.15
CCL7 NM_006273 208075_s_at 0.15 0.20 1.05
CCR8 NM_005201 208059_at 0.42 0.75 0.81
CCL27 NM_006664 207955_at 0.07 0.23 0.18
CCL17 NM_002987 207900_at 0.10 0.08 0.10
CCL22 NM_002990 207861_at 0.27 0.24 0.35
CXCL5 NM_002994 207852_at 0.06 0.06 0.19
CXCL3b,c NM_002090 207850_at 0.42 0.18 27.06
CCR2 NM_000648 207794_at 0.27 0.41 0.48
CXCR3 NM_001504 207681_at 0.23 0.25 0.26
CMKLR1 NM_004072 207652_s_at 0.15 0.09 0.22
CCL1 NM_002981 207533_at 0.14 0.11 0.13
CCR9 AF145439 207445_s_at 0.51 0.63 0.62
CCL16 NM_004590 207354_at 0.24 0.16 0.41
IL8RA NM_000634 207094_at 0.22 0.39 0.40
IL8RB NM_001557 207008_at 0.08 0.06 0.05
CCR5 NM_000579 206991_s_at 0.60 0.13 0.10
CCL25 NM_005624 206988_at 0.15 0.28 0.30
CCR6 NM_004367 206983_at 0.22 0.25 0.36
CCR2 NM_000647 206978_at 1.25 0.92 1.14
CXCR6d NM_006564 206974_at 1.26 0.51 0.41
CCL13 NM_005408 206407_s_at 0.52 0.18 0.54
PF4 NM_002619 206390_x_at 0.39 0.93 1.70
XCL1 U23772 206366_x_at 0.33 0.15 0.22
XCL1 NM_002995 206365_at 0.16 0.52 0.30
CCR7 NM_001838 206337_at 1.54 0.50 0.83
CXCL6b,c NM_002993 206336_at 0.33 0.30 64.72
CX3CR1 U20350 205898_at 0.86 0.16 0.10
CCL20b,c NM_004591 205476_at 0.40 2.90 12.33
CCL15 NM_004166 205392_s_at 3.36 0.77 1.13
CXCL13 NM_006419 205242_at 0.34 0.25 0.09
HM74 NM_006018 205220_at 0.73 0.54 0.50
CCL3b,c NM_002983 205114_s_at 2.20 0.41 0.17
CCR1d NM_001295 205099_s_at 1.59 0.65 0.17
CCR1c,d AI421071 205098_at 2.72 3.28 0.89
CCL5b,c NM_002985 204655_at 2.30 0.77 0.69
CCL21 NM_002989 204606_at 1.05 0.41 0.46
CXCL10 NM_001565 204533_at 2.47 1.50 1.41
CXCL1b,c NM_001511 204470_at 4.40 11.08 144.50
CCL4 NM_002984 204103_at 0.82 0.35 0.13
CXCL9 NM_002416 203915_at 2.61 1.03 1.28
CX3CL1 NM_002996 203687_at 0.32 0.23 0.12
CXCL12 NM_000609 203666_at 2.42 1.34 1.29
CXCL8b,c NM_000584 202859_x_at 2.39 3.49 118.70
CCL5b,c M21121 1405_i_at 0.59 0.05 0.07
a

For each gene, the normalization was performed with Affymetrix 5.1 before importion into GeneSpring and scaling the mean intensity of each sample to 1. Data from 14 different samples (patients) with sporadic LAM, 4 different cultures of Malme-3M, and 8 different cultures of pulmonary artery smooth muscle cells were analyzed.

b

Probes used for clustering in Fig. 1C.

c

Probes used for clustering in Fig. 1B.

d

Probes used for clustering in Fig. 1D.