Table III.
Distribution of the CCL2 gene polymorphismsa
| Single Nucleotide Polymorphism |
No. (%) of Samples | ||
|---|---|---|---|
| LAM | Normal volunteer | ||
| A(−2578)Gb | |||
| AA | 120 (57.1) | 103 (49.0) | |
| AG | 81 (38.6) | 86 (41.0) | |
| GG | 9 (4.3) | 21 (10.0) | |
| A(−2136)Tc | |||
| AA | 140 (70.7) | 115 (58.1) | |
| AT | 51 (25.8) | 77 (38.9) | |
| TT | 7 (3.5) | 6 (3.0) | |
| A(−2578)G | A(−2136)Td | ||
| AA | AA | 70 (35.9) | 43 (22.1) |
| AT | 36 (18.5) | 49 (25.1) | |
| TT | 7 (3.6) | 6 (3.1) | |
| AG | AA | 61 (31.3) | 55 (28.2) |
| AT | 13 (6.7) | 24 (12.3) | |
| TT | 0 | 0 | |
| GG | AA | 8 (4.1) | 15 (7.7) |
| AT | 0 | 3 (1.5) | |
| TT | 0 | 0 | |
a
Samples from 210 LAM patients and 210 healthy-matched volunteers were analyzed.
b
p = 0.018.
c
p = 0.036.
d
p = 0.002.