Table 1.
Characteristic | Infliximab (group A), n = 11 | Surgery (group B), n = 10 | Infliximab + surgery (group C), n = 14 |
---|---|---|---|
Sex, male:female ratio | 4:7 | 3:7 | 6:8 |
Current regular smoker, no. of patients | 4 | 3 | 6 |
Median (range) | |||
Age, yr | 36.3(19–63) | 33.1 (16–58) | 35.3 (18–65) |
Duration of disease, yr | 8.8(1–14) | 7.9 (0.9–18) | 7.4 (0.8–21) |
Duration of fistula, mo | 13.8(6–33) | 14.5 (4–29) | 12.1 (5–42) |
Preoperative PCDAI score | 10.7(7–13) | 11.2 (7–15) | 11.07 (9–16) |
Disease location, no. of patients | |||
Small bowel | 2 | 2 | 3 |
Colon | 4 | 3 | 4 |
Small bowel and colon | 5 | 5 | 6 |
Perianal only | 0 | 0 | 1 |
Previous procedure, no. of patients | |||
Resection for Crohn disease | 5 | 3 | 0 |
Perianal surgery | 3 | 2 | 8 |
Immunomodulator therapy | 11 | 10 | 14 |
Antibiotics | 11 | 10 | 14 |
Anti-TNF-α therapy | 2 | 3 | 1 |
Magnetic resonance imaging | 4 | 3 | 5 |
Endoscopic ultrasonography | 7 | 7 | 9 |
PCDAI = Perianal Crohn’s Disease Activity Index; TNF = tumour necrosis factor.