Table 2.
Outcome of interventions
| Outcome | Infliximab (group A), n = 11 | Surgery (group B), n = 10 | Infliximab + surgery (group C), n = 14 | p value |
|---|---|---|---|---|
| Treatment response, no. of patients* | 0.74 | |||
| No response | 1 | 1 | 1 | |
| Partial response | 3 | 2 | 2 | |
| Complete response | 7 | 7 | 11 | |
| Proctectomy or diversion | 1/11 | 2/10 | 0/14 | 0.2 |
| Healed† | 4/7 | 4/7 | 9/11 | 0.9 |
| Healing time of fistula,† mean (SD), mo | 3.0 (0.8) | 4.2 (1.3) | 3.1 (0.8)‡ | |
| Recurrent fistula | 3/7 | 3/7 | 2/11 | 0.2 |
| Time to relapse, mean (SD), mo | 2.6 (0.7)§ | 3.6 (0.5)§ | 10.1 (2.4) | |
SD = standard deviation.
*
Patients assessed at 6-month follow-up visit.
†
Refers to patients with a complete response.
‡
p < 0.05 v. group B.
§
p < 0.05 v. group C.