Table 1.
HLA haplotypes and characteristics of the cell lines and patients’ and healthy donors’ PBMC used in these studies.
| Cells | HLA-A | HLA-B | HLA-DR | Disease Stage |
Histologic Subtype |
|---|---|---|---|---|---|
| H 292 | A2, A74 | B58, B15 | DR15, DR11 | Squamous cell carcinoma | |
| H182 | All, A* | B15, B35 | DR4, DR11 | Squamous cell carcinoma | |
| H183 | A*, A* | B51, B35 | DR1, DR4 | Large cell carcinoma | |
| H522 | A2, A* | B55, B44 | DR4, DR15 | Adenocarcinoma | |
| H838 | A68, A68 | B18, B35 | DR1, DR1 | Adenocarcinoma | |
| H358 | A*03 | B35 | DR1, DR- | Adenocarcinoma | |
| H177 | A24, A68 | B35, B51 | DR1, DR4 | Large cell carcinoma | |
| Lung fibroblasts | DR1, DR4 | ATCC CCL-202 | |||
| Healthy donor | A33, A36 | B-, B44 | DR1, DR7 | ||
| BC123104(HD1) | |||||
| Healthy donor | All, A29 | B44, B51 | DR4, DR7 | ||
| BC070605 & | |||||
| BC100504(HD2) | |||||
| Healthy donor | A23, A68 | B44, B * | DR7, DR15 | ||
| BC011405(HD3) | |||||
| Healthy donor | A3, A24 | B55, B62 | DR4,- | ||
| BC013103(HD4) | |||||
| Patient#1 | A29, A32 | B44, B60 | DR4,DR7 | IV | Adenocarcinoma |
| Patient#3 | Al | B8, B57 | DR7, DR15 | IIIB | Adenocarcinoma |
| Patient#4 | Al, A2 | B15, B60 | DR1, DR8 | IV | Squamous cell carcinoma |
| Patient#5 | A3 | B7, B- | DR15 | IB | Adenocarcinoma |
| Patient#6 | A2, A24 | B13, B51 | DR4, DR7 | IV | Adenocarcinoma & Squamous carcinoma |
| Patient#9 | A2 | B44, B62 | DR4, DR16 | IV | Adenocarcinoma |
| Patient#10 | A-, All | B7, B44 | DR7, DR15 | IV | Adenocarcinoma |