Table 2.
Correlation of FAK Expression and Clinicopathological Factors
| Factor | FAK-positive (n = 43) | FAK-negative (n = 16) | P Value |
|---|---|---|---|
| Sex (M:F) | 28:15 | 9:7 | 0.897 |
| Age, years (mean ± SD) | 64.0 ± 13.3 | 63.3 ± 14.8 | 0.549 |
| Procedure (gastrectomy) | 0.259 | ||
| Subtotal:total | 32:11 | 13:3 | |
| Tumor size, cm | 4.2 ± 2.3 | 3.9 ± 3.1 | 0.244 |
| Lauren classification | 0.007 | ||
| Intestinal type | 23 | 4 | |
| Diffuse type | 20 | 9 | |
| Mixed type | 0 | 3 | |
| Tumor depth* | 0.175 | ||
| 1:2:3:4 | 7:7:1:8 | 5:2:0:9 | |
| Node metastasis | 0.557 | ||
| No:yes | 13:30 | 5:11 | |
| UICC staging | 0.194 | ||
| I:II:III:IV | 11:4:10:18 | 6:1:5:4 | |
| Recurrence | 0.441 | ||
| No | 25 | 10 | |
| Yes | 18 | 6 |
FAK-positive, overexpressed FAK; FAK-negative, low or nonexpressed FAK; M, male; F, female.
*
Tumor depth: 1, mucosa or submucosa; 2, muscularis propria; 3, subserosa; 4, serosa or extra-serosal involvement.