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. 2010 Oct;177(4):1710–1724. doi: 10.2353/ajpath.2010.090903

Figure 1.

Figure 1

Illustration of TSP1-derived molecules used in vivo and in vitro. Platelet-derived trimeric human thrombospondin-1 (TSP1) (aa 1-1152); recombinant TSP1 N-terminal domain trimer (NoC1; aa 1-356); synthetic CRT-binding TSP1 peptide (hep I; aa 17-35); secreted CRT-binding domain EGFP construct [NTD (1-35)-EGFP; TSP 1 aa1-35] and secreted nonfunctional mutated construct [mod NTD (1-35)-EGFP]; and nonsecreted EGFP parent vector. S indicates signal sequence; EGFP, enhanced green fluorescent protein; TSR, type 1 thrombospondin repeat; 2, type 2 thrombospondin repeat.