Activation of Akt, p38 MAPK, and NF-κB in regenerating TA muscle of control, TWEAK-Tg, and TWEAK-KO mice. A: Representative immunoblots show no apparent differences in levels of phospho-Akt and phospho p38MAPK in regenerating TA muscle of control, TWEAK-Tg, and TWEAK-KO mice. B: DNA-binding activation of NF-κB measured by EMSA was found to be increased in regenerating TA muscle of TWEAK-Tg mice and reduced in TWEAK-KO mice as compared with control mice.