Figure 3.

LD50 Ranges for HJP-272 and HJP-286. LD₅₀s were determined according to the Organization for Economic Development 423 guidelines (Acute Toxic Class Method). Starting dose was 200 mg/kg. Actual mortality is in shaded green ovals, and theoretical mortality is shown in the pink ovals. HJP-272 falls into category 5 (>1000–5000 mg/kg) (A) while HJP-286 falls into category 4 (>200–1000 mg/kg) (B). *, globally Harmonised Classification System (mg/kg b.w.); **, LD₅₀ cut-off (mg/kg b.w.); ∞, unclassified.