Figure 4.

Chronically inflamed hepatic portal region seen in one mouse treated with HJP-272. Mice were administered the compound intraperitoneally and then euthanized 10 days afterward. All vital organs were harvested and preserved in buffered formalin. Sections of the liver from a control mouse, injected with vehicle, are shown in A (original magnification, ×200) and B (original magnification, ×400). Sections of the liver from a mouse exposed to 400 mg/kg HJP-272 are shown in C (original magnification, ×200) and D (original magnification, ×400).