Figure 3.

Relationship between Cdc7 expression, cell cycle phenotype, breast cancer subtype, and disease-free survival. A: The median (solid black line), interquartile range (boxed), and range (enclosed by lines) of Cdc7 expression across the breast cancer series are shown according to cell cycle phenotype (see text and Figure 1). Outlying cases are shown by isolated points. B: Relationship between cell-cycle phenotype and breast cancer subtypes. The panels show the proportion of each breast cancer subtype that display cell-cycle phenotypes I, II, and III. C: Kaplan–Meier curves showing an association between Cdc7 and disease-free survival (months from diagnosis to death, recurrence, or last follow-up) across the whole breast cancer series.