Table 3.

Associations Between Chemokines and Atherosclerosis

	Unadjusted		Adjusted
	OR [95% CI]	P value	OR [95% CI]	P value
CAC (n = 2,435)
CCL23 > median*	1.5 [1.2, 1.8]	0.0001	1.3 [1.0, 1.7]	0.02
Log CCL23 continuous†	1.3 [1.2, 1.4]	<0.0001	1.2 [1.0, 1.3]	0.02
Detectable CXCL1	1.5 [1.1, 2.0]	0.01	1.4 [1.0, 2.1]	0.06
Detectable CXCL2	1.2 [1.0, 1.5]	0.08	1.3 [1.0, 1.6]	0.06
CCL11 > median*	1.1 [0.9, 1.3]	0.56	1.0 [0.8, 1.3]	0.97
Log CCL11 continuous†	1.0 [0.9, 1.1]	0.86	1.0 [0.8, 1.1]	0.48

	Unadjusted		Adjusted
	Beta	P value	Beta	P value
AWT (n = 2,238)
CCL23 > median*	0.034	0.01	−0.001	0.96
Log CCL23 continuous†	0.092	<0.0001	0.021	0.25
Detectable CXCL1	0.019	0.41	0.012	0.55
Detectable CXCL2	−0.002	0.89	0.005	0.71
CCL11 > median*	0.017	0.21	0.000	0.98
Log CCL11 continuous†	0.026	0.23	0.003	0.88
APB (n = 2,223)
CCL23 > median*	0.189	0.03	0.029	0.69
Log CCL23 continuous†	0.133	0.002	0.011	0.76
Detectable CXCL1	0.125	0.38	0.078	0.52
Detectable CXCL2	−0.07	0.45	−0.076	0.34
CCL11 > median*	0.162	0.06	0.043	0.56
Log CCL11 continuous†	0.006	0.88	−0.038	0.30
Aortic compliance (n = 2,355)
CCL23 > median*	−1.054	0.03	−0.098	0.81
Log CCL23 continuous†	−0.063	0.002	−0.001	0.94
Detectable CXCL1	−2.245	0.01	−1.136	0.09
Detectable CXCL2	−1.101	0.04	−0.532	0.22
CCL11 > median*	0.093	0.85	0.141	0.73
Log CCL11 continuous†	−0.005	0.80	−0.005	0.79

^*Non-continuous versions are above/below median.

^†Betas, OR for continuous versions are for 1 standard deviation increase.