Figure 4.

A conserved domain is required for the function of Kuk in nuclear elongation in the early Drosophila embryo. Nuclear morphology of kukΔ15 embryos injected with mRNA of different constructs, at the end of cellularization. The membrane front, stained by Slam (blue) indicates the embryonic stage. Lamin Dm0 (red) or Nup50 (red; D) are used as markers of the NM. (A) FL-Kuk–injected embryo, side view. (A′), surface view. (B) Kuk-cc+ΔN185–injected embryo, side view. (B′) Surface view. (C) Kuk-Δ353-404–injected embryo, side view. The NM blebs are indicated by arrows. (C′) Surface view. (D) HA-LaminDm0–injected embryo, side view. (D′) Surface view. Bar, 10 μm.