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. 2010 Sep 29;5(9):e12722. doi: 10.1371/journal.pone.0012722

Figure 5. States used to compute protein solvation energies.

Figure 5

(A) The helix (orange) is pictured embedded in the membrane, which is delineated by the upper blue and lower gray lines. The membrane core between the two red lines is assigned a dielectric value Inline graphic = 2. A headgroup region of 8 Å is indicated between the water and membrane core. Bulk water above and below the membrane is assigned a dielectric value of Inline graphic = 80. (B) The helix in the bulk water (Inline graphic = 80) in the absence of the membrane. The helix carries one charged residue (Arg14) shown in green in (A) and (B). The protein solvation energy is calculated by computing the total electrostatic energy of systems A and B and then calculating the quantity: Inline graphic. Images rendered with VMD [63].