Table 2. Association of KIF6 Trp719Arg with Myocardial Infarction.
Model 1† | Model 2§ | Model 3‡ | |||||||||
Genotype | Case | Control | OR | 95% CI | p Value | OR | 95% CI | p Value | OR | 95% CI | p Value |
ArgArg + ArgTrp | 1202 | 1251 | 1.10 | 0.97–1.25 | 0.14 | 1.13 | 0.98–1.29 | 0.083 | 1.12 | 0.98–1.28 | 0.10 |
TrpTrp | 785 | 896 | ref | ref | ref | ||||||
ArgTrp | 952 | 966 | 1.13 | 0.99–1.29 | 0.074 | 1.16 | 1.01–1.34 | 0.040 | 1.15 | 1.00–1.33 | 0.049 |
ArgArg | 250 | 285 | 1.00 | 0.83–1.22 | 0.98 | 1.01 | 0.82–1.25 | 0.93 | 1.00 | 0.81–1.24 | 1.00 |
Cases and controls were matched for sex, age (±5 y), and county of residence.
Adjusted for smoking (current vs. never smoked), history of hypertension, history of diabetes, family history of MI, and waist-to-hip ratio.
Adjusted for Model 2 covariates plus admixture.
OR = odds ratio; CI = confidence interval; ref = reference group.