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. Author manuscript; available in PMC: 2011 Oct 1.
Published in final edited form as: Hepatology. 2010 Oct;52(4):1371–1379. doi: 10.1002/hep.23833

Figure 3. Impaired hepatic AKT activation and Mer phosphorylation in GAS6-deficient mice during I/R.

Figure 3

Wild-type or Gas6-/- mice were subjected to hepatic ischemia for 90 minutes and liver protein extracts were obtained for western analysis after 60 minutes of reperfusion. A, JNK activation, B, AKT phosphorylation, C, NF-κB nuclear p65 translocation, and D, GAS6 and phosphorylation of Axl and Mer were analyzed. Representative blots of two independent experiments are shown.