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. Author manuscript; available in PMC: 2011 Oct 1.
Published in final edited form as: Am J Obstet Gynecol. 2010 Aug 5;203(4):385.e1–385.e5. doi: 10.1016/j.ajog.2010.06.017

Figure 1. DHA Treatment after hypoxia ischemia attenuates forepaw placing deficits among hypoxic ischemic pups.

Figure 1

Vibrissae-stimulated forepaw placing (10 trials/side) was evaluated on postnatal-day-14 (P14) in pups that underwent right carotid ligation followed by 90 minutes of hypoxia at 8% oxygen followed by administration of treatment (DHA 1mg/kg, 2.5mg/kg or 5mg/kg) or control (albumin, normal saline (NS)) on P7. The y-axis represents the weighted response score (see Methods; best possible score is 20). Boxes represent interquartile range; horizontal bars represent medians. Whiskers extend to data points no more than 1.5 width of box. There is an overall beneficial effect of DHA treatment when comparing pooled treatment (3 DHA doses) with pooled control groups (NaCl and Albumin (p = 0.035, t-test). ** Vibrissae scores are significantly better with DHA 2.5 mg/kg than 1 mg/kg or either control group (p = 0.032, Tukey Kramer). Because there is minimal variability in treatment groups, the circles represent the artificial distinction of outlier and stars represent extreme values.