Table 3.
Comparison of SGPFC volumes as a function of having a first degree relative with any mood disorder
| HC (n = 41) | PBD with positive family history (n = 33) | PBD with negative family history (n=18) | p** | |
|---|---|---|---|---|
| Mean (SD) | Mean (SD) | Mean (SD) | ||
| R. SGPFC* | 347(125) | 318(126) | 331(116) | 0.62 |
| L. SGPFC* | 400(144) | 318(120) | 409(118) | 0.01 |
All units are mm3
ANCOVA with age, gender, TBV as covariates. For L SGPFC, pairwise comparisons using Sidak correction for multiple comparisons showed that mean volume of HC was significantly larger than that of PBD with positive family history (p = .027). Remaining pairwise differences were not significant.