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. Author manuscript; available in PMC: 2011 Apr 1.
Published in final edited form as: Nat Neurosci. 2010 Sep 5;13(10):1190–1198. doi: 10.1038/nn.2623

Figure 6.

Figure 6

Disruption of Pet-1-dependent transcription in the adult ascending 5-HT system causes elevated anxiety-like behavior. Six to eight-week-old male Pet-1aCKO mice (n=12) and their littermate controls (Pet-1fl/−, n=12) were treated with TM for 5 consecutive days and then acclimated for another 4 weeks before behavioral testing. (a–e) Elevated plus maze, * p<0.05, ** p<0.01, *** p<0.001; two tailed t test. (f–h) Dark ↔ light exploration, * p<0.05, ** p<0.01; two tailed t test. (i, j) Open field, * p<0.05; two tailed t test. Error bars represent s.e.m.