Table 2.
Multivariate Cox proportional hazards analysis of the association of rs8099917 genotypes with spontaneous HCV clearance, adjusted for sex and symptomatic infection, during recent infection, excluding treated participants with an estimated duration of infection <26 weeks.
| Covariate | AHR | 95% | CI | P |
|---|---|---|---|---|
| Sex | ||||
| Male | 1.00 | - | - | - |
| Female | 1.81 | 0.67 | 4.85 | 0.241 |
| Presentation of recent HCV | ||||
| Asymptomatic seroconversion | 1.00 | - | - | - |
| Acute clinical (no jaundice) | 0.85 | 0.25 | 2.84 | 0.788 |
| Acute clinical (with jaundice) | 1.72 | 0.54 | 5.51 | 0.361 |
| IL28B genotype | ||||
| rs8099917 | ||||
| GG/GT | 1.00 | - | - | - |
| TT | 3.78 | 1.04 | 13.76 | 0.044 |