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Multivariate analysis: factors associated with decreased overall survival
| Factor | Hazard ratio (95% CI) | P value |
|---|---|---|
| Metastases | 20.2 (11.8, 34.5) | < 0.001 |
| Local recurrence | 32.4 (9.9, 105.3) | < 0.001 |
| Male versus female | 0.4 (0.2, 0.6) | < 0.001 |
| Age at diagnosis | 1.1 (1.0, 1.1) | < 0.001 |
| AJCC Stage III versus Stages I and II | 2.6 (1.4, 4.8) | 0.004 |
CI = confidence interval; AJCC = American Joint Committee on Cancer.
