Table 1.

Clinical data for 26 patients with osteosarcoma in Paget’s disease of bone

Age (years)	Gender	Paget’s disease	Tumor location	Surgical treatment	Lung metastases	Chemotherapy and/or radiotherapy	Oncologic result
58	Male	Monostotic	Proximal humerus	Amputation	At diagnosis	CHT	Died
47	Male	Monostotic	Proximal humerus	Amputation	At diagnosis	CHT + Radio	Died
75	Male	Monostotic	Ilium	No surgery	At diagnosis	Radio	Died
60	Male	Monostotic	Proximal tibia	Amputation	At diagnosis	CHT	Died
62	Male	Monostotic	Proximal femur	Amputation	At diagnosis	–	Died
74	Male	Monostotic	Distal femur	Reconstruction	At diagnosis	CHT	Died
57	Female	Monostotic	Pelvis	Amputation	At diagnosis	–	Died
62	Male	Monostotic	Proximal humerus	Amputation	At diagnosis	Radio	Died
75	Male	Monostotic	Proximal femur	No surgery	At diagnosis	Radio	Died
68	Male	Monostotic	Proximal humerus	Reconstruction	At diagnosis	CHT	Died
64	Male	Monostotic	Proximal femur	Amputation	At diagnosis	CHT	Died
54	Male	Poliostotic	Proximal tibia	No surgery	At diagnosis	CHT	Died
67	Male	Monostotic	Proximal femur	Amputation	At diagnosis	CHT	Died
76	Female	Monostotic	Distal femur	Reconstruction	After 10 months	–	Died
66	Male	Poliostotic	Distal femur	Reconstruction*	After 6 months	CHT + Radio	Died
47	Male	Monostotic	Proximal fibula	Resection	After 35 months	CHT	Died
66	Male	Poliostotic	Proximal humerus	Amputation	After 72 months	CHT	Died
65	Male	Monostotic	Distal femur	Amputation	No	CHT	Died
67	Male	Monostotic	Proximal humerus	Reconstruction	No	–	Died
80	Male	Monostotic	Acromion	Amputation	No	–	Died
53	Male	Poliostotic	Calcaneus	Amputation	No	CHT	Alive
58	Female	Poliostotic	Calvaria	Amputation	No	CHT + Radio	Died
75	Female	Monostotic	Proximal tibia	Reconstruction	No	–	Alive
52	Male	Poliostotic	S1–S2	No surgery	No	CHT	Died
38	Male	Poliostotic	Proximal humerus	Amputation	No	CHT	Alive
68	Female	Monostotic	Proximal tibia	Amputation	No	CHT	Alive

*This patient developed a local recurrence after 13 months and underwent amputation; CHT = chemotherapy; Radio = radiotherapy.