Table 2.

Comparison of data from major series of sarcomas in Paget disease reported in the literature and our data

Study	Number of patients	Mean age (years)	DWD/time	NED/time	Metastases	Monostotic/polyostotic disease	Appendicular/axial involvement
Moore et al. [22]	22	71	20/5 days to 2.5 years	1/5 years	–	7/15	16/5 (one patient had multifocal Paget osteosarcoma)
Mankin et al. [19]	40	68 ± 13	5/2.5 years	–	14	–	25/18
Deyrup et al. [7]	70	66	40/1 month to 20 years	3 (3 months, 20 and 21 years)	32	33/37	32/38 (two patients had multifocal osteosarcoma)
Mangham et al. [18]	32	73.1 ± 7.9	31/9 days to 10 years	1 (at 10 years)	–	13/32	22/10
Ruggieri et al. [current study]	26	64	22/1 month to 7 years	4 (3.6, 9.2, 12, and 21 years)	17	19/7	21/5

DVD = dead of disease; NED = no evidence of disease.