Figure 2. Polyene GT-catalyzed Sugar Exchange Reactions.
(A) Schematic of polyene GT-catalyzed sugar exchange reaction. (B) HPLC analyses of AmphDI-T2 catalyzed sugar exchange reactions. In this study, 20 μM AmB (1) was co-incubated with 5 μM of AmphDI-T2 in the presence of 1 mM of (i) GDP-α-D-altrose (18), (ii) GDP-α-D-talose (19), (iii) GDP-β-L-gulose (17), (iv) GDP-β-L-mannose (20), (v) GDP-α-D-glucose (21), (vi) GDP-β-L-glucose (23), (vii) GDP-α-D-mannose (22).