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. Author manuscript; available in PMC: 2011 Nov 10.
Published in final edited form as: Virology. 2010 Aug 24;407(1):68–79. doi: 10.1016/j.virol.2010.07.047

Figure 4. Coreceptor preference of representative chimeric proviruses.

Figure 4

A. Coreceptor usage of 42-month and 48-month variants of child 1690 was determined by entry inhibition into TZM-bl cells with 1 μM CXCR4 inhibitor (AMD 3100) or CCR5 inhibitor (TAK-779). Viruses SF128A, NL4-3 and 89.6 served as controls for CCR5, CXCR4 or CCR5/CXCR4 usage virus, respectively. B, C. Infection and blocking with cognate coreceptor inhibitor were performed in U373-MAGI-CCR5 (B) or U373-MAGI-CXCR4 (C) cells. Viruses SF128A, NL4-3 and 89.6 served as controls for CCR5, CXCR4 or CCR5/CXCR4 usage virus, respectively. The data are expressed as mean values from experiments performed in triplicate, and the error bars indicate standard deviations.