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. Author manuscript; available in PMC: 2011 Nov 10.
Published in final edited form as: Virology. 2010 Aug 24;407(1):68–79. doi: 10.1016/j.virol.2010.07.047

Figure 7. Effects of V3 mutations on coreceptor usage of unrelated subtype C HIV-1.

Figure 7

A. The predicted V3 amino acid sequences of a 48-month variant of child 1984 and the V3 mutant. MT-2 infection was monitored for syncytia formation at day 6 post-infection. B. The coreceptor utilization of the 48-month parental variant and the V3 mutant was determined in U373-MAGI target cells expressing CD4 and either CCR5 or CXCR4. Infection with virus SF128A, NL4-3 and 89.6 served as controls for CCR5, CXCR4 or CCR5/CXCR4 usage virus, respectively. The results are representative of two independent experiments, and the error bars represent standard deviations.