|
Independent variables
|
|
time |
second |
|
time |
day |
|
Dependent variables
|
|
density of merozoites |
|
|
density of uRBCs |
|
|
density of singly-parasitised RBCs |
|
|
density of multiply-parasitised RBCs |
|
|
parasite density (singly-parasitised RBCs) |
|
|
parasite density (multiply-parasitised RBCs) |
|
|
total RBC density on day 
|
|
|
Functions
|
|
immune-mediated clearance rate of merozoites on day 
|
|
|
immune-mediated clearance rate of pRBCs on day 
|
|
|
immune-mediated clearance rate of uRBCs on day 
|
|
|
|
|
|
Parameters
|
|
burst size |
parasites |
|
rate of upregulation of erythropoiesis |
|
|
time delay before upregulation |
day |
|
time lag in erythropoiesis |
day |
|
normal RBC density |
|
|
initial parasite density |
|
|
natural death rate of RBCs |
|
|
increased death rate of multiply-parasitised RBCs |
|
|
infection rate |
|
|
natural loss rate of merozoites |
|
|
|
|
|
maximum level of merozoite-targeting immunity |
|
|
maximum clearance rate of pRBC-targeting immunity |
|
|
maximum clearance rate of uRBC-targeting immunity |
|
|
start day of merozoite-targeting immunity |
day |
|
start day of pRBC-targeting immunity |
day |
|
start day of uRBC-targeting immunity |
day |
|
rise time of merozoite-targeting immunity |
day |
|
rise time of pRBC-targeting immunity |
day |
|
rise time of uRBC-targeting immunity |
day |
|
duration of merozoite-targeting immunity |
day |
|
duration of pRBC-targeting immunity |
day |
|
duration of uRBC-targeting immunity |
day |
