Table 4. The single nucleotide polymorphisms (SNPs) predictive of the subjects with 15% lowest and highest IMT changes from 2001 to 2007.
SNP ID* (rs number) | Gene symbol (HGNC name) | SNP location (Chr region) | Significance† (p-value) | Predictive power‡ (%AUC) |
rs2073658 | USF1 | 1q23.3 | 0.70 | 9.40 |
rs9479055 | C6orf97 | 6qs25.1 | 0.40 | 8.55 |
rs17672135 | FMN2 | 1q43 | 0.41 | 8.55 |
rs9687339 | MAST4 | 5q12.3 | 0.93 | 7.69 |
rs1042713 | ADRB2 | 5q33.1 | 0.48 | 7.69 |
rs2301880 | WNK1 | 12p13.33 | 1.00 | 6.84 |
rs3130340 | INTERGENIC | 6p21.32 | 0.11 | 6.84 |
rs2476601 | PTPN22 | 1p13.2 | 0.44 | 5.13 |
rs11898505 | SPTBN1 | 2p16.2 | 0.27 | 5.13 |
rs3798220 | LPA | 6q25.3 | 1.00 | 5.13 |
rs10172036 | ICOS | 2q33.2 | 0.52 | 5.13 |
rs2820037 | INTERGENIC | 1q43 | 0.66 | 4.27 |
rs2234693 | ESR1 | 6q25.1 | 0.74 | 3.42 |
rs1800896 | IL10 | 1q32.1 | 0.71 | 3.42 |
rs17222814 | ALOX5AP | 13q12.3 | 0.89 | 3.42 |
rs1801274 | FCGR2A | 1q23.3 | 0.75 | 2.56 |
rs854560 | PON1 | 7q21.3 | 0.81 | 1.71 |
rs10246939 | TAS2R38 | 7q34 | 0.80 | 1.71 |
rs9594738 | INTERGENIC | 13q14.11 | 0.58 | 1.71 |
rs1799983 | NOS3 | 7q36.1 | 0.06 | 0.855 |
rs1256049 | ESR2 | 14q23.2 | 0.46 | 0.855 |