Table 2. Compounds Unrelated to FLC That Do Not Compete for Inhibition of FLC Import.
| Sugars | Inositol, Mannose, Galactose, Glucose, Sucrose, beta 1–3 glucan (laminarin) |
| Nucleosides/Bases | Adenosine, Thymidine, Guanosine, Cytosine, Uracil |
| Amino acids | Cas-amino acids, Arg, Pro, His (H), Phe (F) |
| Oligopeptides | HF, FH, HAF, FAH, HAAF, FAAH, HAAAF, FAAAH |
| Non-azole antifungals | 5FC, Amphotericin B, Terbinafine, Fenpropimorph |
| Polyamines | Spermidine, Spermine, Ornithine |
| Sterol Related | Ergosterol, Farnesol, Dialkyl imidazole STN54a |
| Salts | CaCl2, CuSO4, FeSO4, K2SO4, MgSO4, NaCl, and NH4SO4 |
| Unrelated Drugs | DNP (2,4-Dinitrophenol, oxidative phosphorylation inhibitor), CCCP (Carbonyl cyanide m-chlorophenyl hydrazone, oxidative phosphorylation inhibitor), Brefeldin A (transport inhibitor), Rhodamine 6G (competes for efflux pumps) |
All compounds were tested in the standard assay at 100x molar excess to [3H] FLC and had no effect.
a
STN54 is a dialkylimidazole with very potent activity against C14-demethylease, the target of the azole drugs [24].