Table 1. Sources of genes mutated in different cancer types.
Name of study | Tumour type(s) screened |
---|---|
Databases | |
Cancer Gene Census (Futreal et al, 2004) | Many |
OMIM (Hamosh et al, 2005) | Many |
COSMIC (Forbes et al, 2008) | Many |
Gene-set resequencing studies | |
Bardelli et al (2003) | Colorectal |
Wang et al (2004) | Colorectal |
Stephens et al (2005) | Breast |
Davies et al (2005) | Lung |
Greenman et al (2007) | Many |
Thomas et al (2007) | Many |
Loriaux et al (2008) | Acute myeloid leukaemia |
Tomasson et al (2008) | Acute myeloid leukaemia |
Cancer Genome Atlas (Research Network, 2008) | Glioblastoma |
Ding et al (2008) | Lung |
Whole-genome resequencing studies | |
Wood et al (2007) | Breast and colorectal |
Jones et al (2008) | Pancreas |
Ley et al (2008) | Acute myeloid leukaemia |
Parsons et al (2008) | Glioblastoma |
Pleasance et al (2010b) | Lung |
Pleasance et al (2010a) | Melanoma |
Dalgliesh et al (2010) | Renal |
COSMIC, Catalogue of Somatic Mutations in Cancer; OMIM, Online Mendelian Inheritance in Man. |