| Cellular pathways |
| Adipocytokine signalling pathway (hsa04920) |
Colorectal |
ACSL4 ACSL5 AKT1 CAMKK2 CHUK MTOR IRS2 IRS4 JAK1 MAPK9 PRKCQ PTPN11 STK11 TYK2 |
| |
Lung |
AKT1 CAMKK2 CHUK MTOR IKBKB IRS1 IRS4 JAK1 JAK2 JAK3 PPARGC1A PRKCQ PTPN11 RELA STAT3 STK11 TYK2 |
| CBL-mediated ligand-induced downregulation of EGF receptors (h_cblPathway) |
Leukaemia |
CBL CSF1R EGFR MET PDGFRA |
| Epithelial cell signalling in Helicobacter pylori infection (hsa05120) |
Lung |
CHUK CSK CXCR2 EGFR IKBKB MAP2K4 MAP3K14 MAPK11 MAPK14 MAPK8 MET PLCG1 PLCG2 PTPN11 PTPRZ1 RELA SRC |
| NF-κB activation by non-typeable Hemophilus influenzae (h_nthiPathway) |
Lung |
CHUK CREBBP EP300 IKBKB MAP2K6 MAP3K14 MAPK11 MAPK14 RELA SMAD4 TGFBR1 TGFBR2 |
| GnRH signalling pathway (hsa04912) |
Colorectal |
ADCY8 ADCY9 CAMK2A CAMK2B EGFR GNAS HRAS KRAS MAP2K4 MAP2K7 MAP3K2 MAP3K3 MAPK9 MMP2 NRAS PLA2G2A PRKCA PRKCB SRC |
| |
Lung |
CAMK2G EGFR GNAS HRAS ITPR2 KRAS MAP2K4 MAP2K6 MAP3K2 MAP3K3 MAP3K4 MAPK11 MAPK14 MAPK7 MAPK8 MMP2 NRAS PLCB1 PRKACA PRKACB PRKCB PRKCD PRKX RAF1 SRC |
| Regulation of transcriptional activity by PML (h_pmlPathway) |
Leukaemia |
CREBBP HRAS KRAS NRAS PML RARA RB1 TP53 |
| |
Melanoma |
CREBBP DAXX HRAS KRAS NRAS RB1 TNF TNFRSF1A TP53 |
| Trefoil factors initiate mucosal healing (h_tffPathway) |
Lung |
AKT1 CSH2 CTNNB1 CYCS EGFR ERBB2 GHR HRAS KRAS MUC2 NRAS PTK2 SHC1 SOS1 |
| Bioactive peptide induced signalling pathway (h_biopeptidesPathway) |
Lung |
CAMK2G CDK5 FYN HRAS JAK2 KRAS MAPK14 MAPK8 NRAS PLCG1 PRKCB RAF1 SHC1 SOS1 STAT5A |
| Processes |
| Huntington disease (hsa05040) |
Leukaemia |
CLTC CLTCL1 CREBBP EP300 HIP1 TP53 |
| Base-excision repair (GO:0006284) |
Lung |
CKN2 MBD4 MSH6 NTHL1 PCNA POLG RAD51L3 TP53 |
| Double-stranded break repair through non-homologous end joining (GO:0006303, GO:0000726) |
Melanoma |
POLA1 PRKDC XRCC4 XRCC6 |
| Cytokinesis (GO:0000910) |
Lung |
ARHGEF11 AURKB AURKC BRCA2 DIAPH2 ESPL1 INCENP MYH9 ROCK1 |
| Protein import into nucleus, translocation (GO:0000060) |
Leukaemia |
ARNT BCL3 BCL6 JAK2 |
| Protein import into nucleus, translocation (GO:0000060) |
Leukaemia |
ARNT BCL3 BCL6 JAK2 |
| Regulation of protein export from nucleus (GO:0046825) |
Lung |
BARD1 GSK3B PTPN11 |
| Protein domains |
| BRK (IPR006576) |
Lung |
CHD5 CHD6 CHD9 SMARCA4 |
| Bromodomain (IPR001487) |
Brain |
BRD2 EP300 KAT2B MLL PHIP SMARCA2 SMARCA4 SP100 TAF1 TAF1L TRIM24 TRIM33 ZMYND8 |
| |
Lung |
BAZ1A CREBBP EP300 MLL SMARCA4 TAF1 TAF1L TRIM24 TRIM33 |
| Helicases (IPR014001, IPR001650, IPR014021) |
Breast |
ATRX BRIP1 CHD1 CHD5 CHD7 CHD8 CHD9 DDX10 DDX18 DDX3X DDX59 EIF4A2 ERCC3 ERCC6 FANCM HELQ RAD54L SKIV2L SMARCAD1 SMARCAL1 |
| |
Melanoma |
ATRX CHD6 CHD8 DDX24 DDX28 DDX3X DDX4 DDX54 DICER1 POLQ RAD54L SMARCA1 SMARCA4 SMARCA5 SMARCAD1 SMARCAL1 SNRNP200 |
| Diacylglycerol kinase (IPR000756, IPR001206) |
Melanoma |
CERKL DGKB DGKD DGKG DGKZ |
| Laminin G (IPR001791, IPR012680) |
Pancreas |
CELSR1 CNTNAP4 COL11A1 COL5A1 FAT1 FAT3 FAT4 LAMA1 LAMA4 LAMA5 NRXN3 |
| CBL, Casitas B-lineage lymphoma; EGF, epidermal growth factor; GnRH, gonadotropin-releasing hormone; GO, gene ontology; PML, promyelocyclic leukaemia. |
