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. Author manuscript; available in PMC: 2011 Oct 15.
Published in final edited form as: J Comp Neurol. 2010 Oct 15;518(20):4213–4225. doi: 10.1002/cne.22449

Figure 2.

Figure 2

Neuregulin-1 expression in the cervical spinal cord.

A. Montage of maximum intensity projections from multiple confocal image stacks obtained from a transverse section of the spinal cord (C4–C5). The NRG1 immunoreactivity (black) is punctate on the perimeter of large neurons in Rexed's laminae VIII and IX of the ventral horn of the spinal cord. The background was set to permit visualization of the gray matter in the spinal cord (orientation: dorsal is at the top of the image). This pattern of NRG1 immunoreactivity is suggestive of its presence on the surface of motoneurons. Bar: 100 μm.

B. Maximum intensity projection of three confocal slices containing the neuron marked by asterisk in A. The gray level scheme was inverted to optimize visualization of NRG1 in this figure. Note that NRG1 puncta are found predominantly at the soma and primary dendrites of large neurons, likely motoneurons. Bar: 25 μm.