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. 2010 Sep 28;10:e61.

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Copyright © 2010 The Author(s)

This is an open-access article whereby the authors retain copyright of the work. The article is distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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(a) The image shows the cross-section of a skin tissue sample (hematoxylin and eosin staining) that was exposed to plasma-treated collagen-coated silicone implant. (E = epidermis, D = dermis, S = subcutis, M = striated skin muscle, C = capsule). Leukocytes (arrows) penetrate the skin muscle layer (M) directed to the capsular tissue (C). Macrophages (MaPh) are evident at the capsule-muscle interface (magnification: 100-fold). (b) An extensive fibrous deposition within the implant capsule and enhanced infiltration of the capsular tissue by leukocytes were found in the untreated group (magnification: 200-fold). (c) The muscle and the fibrous capsular layer of treated implants show a high vascular infiltration (blood vessels are marked by triangles). Macrophages (MaPh) and a foreign-body giant-cell (FBGC) are detected within the muscle layer. The inflammatory cells are directed towards implant's capsule (magnification: 200-fold).

(a) The image shows the cross-section of a skin tissue sample (hematoxylin and eosin staining) that was exposed to plasma-treated collagen-coated silicone implant. (E = epidermis, D = dermis, S = subcutis, M = striated skin muscle, C = capsule). Leukocytes (arrows) penetrate the skin muscle layer (M) directed to the capsular tissue (C). Macrophages (MaPh) are evident at the capsule-muscle interface (magnification: 100-fold). (b) An extensive fibrous deposition within the implant capsule and enhanced infiltration of the capsular tissue by leukocytes were found in the untreated group (magnification: 200-fold). (c) The muscle and the fibrous capsular layer of treated implants show a high vascular infiltration (blood vessels are marked by triangles). Macrophages (MaPh) and a foreign-body giant-cell (FBGC) are detected within the muscle layer. The inflammatory cells are directed towards implant's capsule (magnification: 200-fold).