Table 1.
Clinical characteristics by BMI categories
| Underweight (n = 281) | Normal (n = 1,627) | Overweight (n = 1,605) | Obese (n = 868) | Total (n = 4381) | Overall P* | Obese vs normal P† | |
|---|---|---|---|---|---|---|---|
| Histologic grade‡ | 0.1370 | 0.6825 | |||||
| 1/2 | 124 (68.9%) | 763 (73.5%) | 786 (76.1%) | 388 (74.5%) | 2,061 (74.4%) | ||
| 3/4 | 56 (31.1%) | 275 (26.5%) | 247 (23.9%) | 133 (25.5%) | 711 (25.6%) | ||
| Stage | 0.0129 | 0.0516 | |||||
| III | 200 (71.7%) | 1,235 (76%) | 1,219 (76.1%) | 684 (79.4%) | 3,338 (76.5%) | ||
| II | 79 (28.3%) | 390 (24%) | 382 (23.9%) | 177 (20.6%) | 1,028 (23.5%) | ||
| Tumor site | 0.0144 | 0.0575 | |||||
| Distal | 78 (43.3%) | 497 (47.9%) | 512 (49.7%) | 275 (53%) | 1,362 (49.2%) | ||
| Proximal | 102 (56.7%) | 541 (52.1%) | 518 (50.3%) | 244 (47%) | 1,405 (50.8%) | ||
| MMR | 0.0082 | 0.0347 | |||||
| Intact | 40 (75.5%) | 339 (84.5%) | 370 (85.1%) | 201 (90.5%) | 950 (85.5%) | ||
| Defective | 13 (24.5%) | 62 (15.5%) | 65 (14.9%) | 21 (9.5%) | 161 (14.5%) | ||
| Gender | <0.0001 | 0.6163 | |||||
| Women | 205 (73%) | 840 (51.6%) | 623 (38.8%) | 439 (50.6%) | 2,107 (48.1%) | ||
| Men | 76 (27%) | 787 (48.4%) | 982 (61.2%) | 429 (49.4%) | 2,274 (51.9%) | ||
| Age | 0.0005 | 0.0382 | |||||
| Mean (SD) | 57.8 (14.25) | 61.0 (12.11) | 61.7 (10.50) | 60.6 (10.24) | 61.0 (11.38) | ||
| Median | 60.5 | 63.0 | 63.0 | 61.3 | 62.1 | ||
| Range | 18.0–84.2 | 18.3–89.0 | 22.0–89.7 | 23.7–83.3 | 18.0–89.7 | ||
| Treatment status | 0.0349 | 0.0293 | |||||
| Ineffective | 81 (28.8%) | 438 (26.9%) | 437 (27.2%) | 199 (22.9%) | 1,155 (26.4%) | ||
| Effective | 200 (71.2%) | 1,189 (73.1%) | 1,168 (72.8%) | 669 (77.1%) | 3,226 (73.6%) | ||
| Lymph nodes | 0.0714 | 0.0171 | |||||
| 0 | 66 (28.2%) | 333 (25.9%) | 342 (27.4%) | 148 (23.8%) | 889 (26.2%) | ||
| 1–3 | 113 (48.3%) | 670 (52.1%) | 632 (50.6%) | 299 (48.1%) | 1,714 (50.5%) | ||
| >3 | 55 (23.5%) | 284 (22.1%) | 275 (22%) | 174 (28%) | 788 (23.2%) | ||
| T stage | 0.3508 | 0.8280 | |||||
| T1,2 | 19 (8.4%) | 141 (10.9%) | 145 (11.5%) | 71 (11.3%) | 376 (11%) | ||
| T3,4 | 206 (91.6%) | 1,148 (89.1%) | 1,115 (88.5%) | 559 (88.7%) | 3,028 (89%) |
*
Kruskal-Wallis test for continuous data; Χ2 test for variables with 3+ categories; Cochran-Armitage test for trend P value for variables with only 2 categories.
†
Χ2 test for categorical data and Wilcoxon rank-sum test for continuous data.
‡
Grade1/2: well/moderate differentiation; grade 3/4: poor/undifferentiated.