Table 1. Significant biological pathways associated with each major group of clustered gene expression profiles.
| Increased Expression Group (2111 genes) | Gene List Hits | Gene Total Hits | Fisher Exact p-value |
| ECM-receptor interaction | 26 | 59 | 3.33×10−11 |
| Focal adhesion | 43 | 161 | 3.43×10−9 |
| Cell Communication | 23 | 82 | 7.92×10−6 |
| Matrix Metalloproteinases | 8 | 17 | 2.36×10−5 |
| Cell adhesion molecules (CAMs) | 26 | 111 | 6.73×10−5 |
| Wnt Signaling | 8 | 25 | 6.07×10−4 |
| Colorectal cancer | 16 | 70 | 2.28×10−3 |
| Arginine and proline metabolism | 8 | 24 | 2.50×10−3 |
| Adherens junction | 14 | 62 | 4.76×10−3 |
| Bladder cancer | 9 | 32 | 4.97×10−3 |
| Axon guidance | 19 | 96 | 5.27×10−3 |
| TGF Beta Signaling Pathway (GenMAPP) | 7 | 28 | 6.66×10−3 |
| Inflammatory Response Pathway | 6 | 22 | 7.71×10−3 |
| Alzheimer's disease | 7 | 25 | 1.32×10−2 |
| TGF-beta signaling pathway (KEGG) | 14 | 70 | 1.43×10−2 |
| Blood Clotting Cascade | 3 | 7 | 1.64×10−2 |
| Orphan GPCRs | 3 | 8 | 2.46×10−2 |
| Basal cell carcinoma | 9 | 42 | 3.03×10−2 |
| Melanogenesis | 14 | 79 | 3.81×10−2 |
| Antigen processing and presentation | 11 | 58 | 4.05×10−2 |