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. 2010 Oct 1;5(10):e13099. doi: 10.1371/journal.pone.0013099

Table 2. Levels of chemokines and cytokines in the peripheral blood.

Values represent Median log10pg/ml (range)
Critically ill patients p Valuea p Valueb Mild cases p Valuec Healthy Controls Lung Aspirates
Pro-Inflammatory Cytokines
IL1α 1.64 (−0.70–3.26) 0.2061 0.0032 −0.70 (−0.70–3.26) 0.0312 −0.70 (−0.70–3.28) 2.81 (0.48–3.21)
IL1β 0.48 (−0.70–1.05) 0.2639 0.0053 0.32 (−0.70–1.80) 0.0006 −0.70 (−0.70–0.72) 2.05 (0.48–2.68)
IL6 2.14 (0.40–3.11) 0.0022 0.0000 0.32 (−0.70–3.11) 0.0001 Undetected 2.59 (0.48–3.29)
TNFα 0.48 (0.48–1.06) 0.3697 0.0000 0.70 (−0.70–4.41) 0.0000 Undetected 0.48 (0.48–0.48)
IL17 0.48 (−0.70–2.14) 0.2608 0.0002 0.18 (0.08–1.62) 0.0000 −0.70 (−0.70–0.61) 0.48 (0.48–1.07)
Anti-Inflammatory Cytokines
IL1RA 1.23 (−0.70–3.20) 0.0220 0.0000 0.82 (−0.70–1.84) 0.0001 Undetected 2.55 (0.48–3.01)
IL2RA 0.91 (−0.01–1.18) 0.4438 0.0000 −0.10 (−0.10–2.92) 0.0000 Undetected 2.27 (0.48–2.58)
IL10 1.71 (−0.70–2.59) 0.0135 0.0000 −0.70 −0.70–2.38) 0.0011 Undetected 0.48 (0.48–2.59)
Th-1 Cytokines
IL2 0.48 (0.01–1.31) 0.0002 0.0000 −0.70 (−0.70–0.53) 0.0032 Undetected 0.48 (0.48–2.52)
IL12p70 0.26 (−0.70–0.32) 0.6705 1.0000 0.20 (0.05–0.32) 0.4417 0.20 (0.05–0.32) 0.48 (0.48–2.74)
IL12p40 0.48 (−0.70–2.76) 0.2655 0.0000 0.32 (0.08–2.18) 0.0000 Undetected 2.40 (0.48–2.74)
Chemokines
CXCL5 3.30 (−0.70–3.71) 0.1580 0.0001 −0.70 (−0.70–3.55) 0.0039 Undetected 2.92 (1.13–3.78)
CXCL8 1.37 (−0.70–3.63) 0.5150 0.0000 1.10 (0.20–3.65) 0.0000 Undetected 4 (0.48–4.04)
MIF 3.33 (3.13–4.24) 0.4368 0.0072 3.45 (3.13–4.05) 0.0009 3.08 (2.11–3.69) 4.18 (1.08–5.42)
CCL3 1.66 (−0.70–2.25) 0.0224 0.0000 −0.70 (−0.70–2.28) 0.0032 Undetected 1.54 (0.48–2.80)
CCL4 1.89 (−0.70–2.84) 0.0495 0.0000 1.57 (−0.70–2.0) 0.0001 Undetected 2.59 (0.08–3.43)
TRAIL 0.15 (−0.70–3.09) 0.2866 0.0032 0.15 (−0.70–3.09) 0.0012 −0.70 (−0.70–3.51) 1.89 (−0.30–2.76)

a* p value between critically ill patients and mild cases.

b* p values between critically ill patients and healthy controls.

c* p values between mild cases and healthy controls.