Figure 5. Most genes have cot-groups with at least 2 members.

A: Distribution of the maximum cot-group size for the 99 analyzed genes. For each cot-group with the indicated number of members on the x-axis, the number of genes where counted that have cot-groups with a corresponding maximum cot-group size. This shows for example that there are 19 genes that have cot-groups with no more than 2 members. Most genes (38) in our analysis appear to have at least one cot-group present with up to 3 members. Due to the correlation between gene length and number of cot-groups, some large genes in our analysis also show very large cot-groups which account for the unexpected large 7+ count as plotted in the last bar (see also Figure 2 and Supporting Information S1). B: The results after filtering out intron targets are presented, showing that most genes have at least one cot-group with 2 members.