Table 2. VAR2CSA-DBL5ε residues Q303, E303 and K303 distribution in relation to placental parasite CSA/CSPG binding affinity.
Q303 | E303 | K303 | |
Isolates | |||
High binders (n = 20) | 10/20a | 6/20 | 6/20 |
Low binders (n = 16) | 1/16 | 7/16 | 9/16 |
Those parasites ability to bind CSA or CSPG have previously been described [2].
p<.01, t-test.
n corresponds to placental parasite isolates.