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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: J Immunol. 2006 Dec 1;177(11):8202–8211. doi: 10.4049/jimmunol.177.11.8202

Figure 2. RT-PCR of IRAK-4 revealed a splice variant.

Figure 2

RT-PCR of partial IRAK-4 transcripts using PBMC mRNA amplified the expected 660 bp product and a 574 bp product in both patient and control samples. Both products from the patient and a control were sequenced, and the 574 bp product revealed an 86 bp deletion at the end of exon-5, resulting in a premature stop codon.