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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: J Immunol. 2006 Dec 1;177(11):8202–8211. doi: 10.4049/jimmunol.177.11.8202

Figure 4. Defective cytokine responses in IRAK-4-deficient PBMC.

Figure 4

Primary PBMC from the patient and controls were exposed to 100 ng/ml each of LPS, IL-1β, or TNF-α, or unstimulated and incubated at 37°C in 5% CO2 for 24 hr. Supernatants were examined by ELISA, for IL-6 (a) and IL-8 (b). Mean (± SEM) from n≥3 repeats for each stimulus, with n=3 replicates per study. ** p < 0.01, * p<0.05.