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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: J Immunol. 2009 Jul 13;183(3):2122–2132. doi: 10.4049/jimmunol.0804187

Figure 4. Necrotic neutrophils but not other necrotic cells are anti-inflammatory.

Figure 4

Apoptotic neutrophils (N), necrotic neutrophil supernatants (NN), necrotic thymocyte supernatants (NT) and necrotic supernatants from the tumour cell line Mutu (NM) were added to either LPS (a) or CD40L/IFN-γ (CI) (b) stimulated macrophages and culture supernatants collected 18 hours later were analysed by ELISA for TNF-α. Murine bone marrow derived macrophages were also stimulated with either LPS (c) or CD40L/IFN-γ [CI] (d) with added NN or NT and culture supernatants tested for NO by the Griess reaction. *** p ≤0.0001, ** p ≤0.002, * p ≤0.02.error bars =SEM.