Figure 6. Co-treatment with BZ and PS inhibits in vivo tumor growth in Z138C xenografts.
A, Regression of tumor volume (n=8) following treatment with PS, BZ and a combination of BZ and PS is depicted. B, Kaplan-Meier survival plot for a Z138C xenograft model of MCL: NOD-SCID mice (n=8/group) were injected with Z138C cells subcutaneously and treatment with BZ, PS and the combination was commenced when the average tumor volume reached 50 mm3.