Table 1.

Panobinostat and/or BZ induces cell death of primary MCL cells

	% cell death of primary MCL samples
sample	control	25 nM, BZ	50 nM, PS	BZ + PS
Normal CD34+	2.8 ± 0.2	9.3 ± 3.8	30.1 ± 2.0	33.5 ± 3.0
MCL#1	2.7 ± 0.2	5.4 ± 0.3	10.1 ± 1.6	25.6 ± 1.7 *
MCL#2	4.9 ± 2.0	27.7 ± 4.1	41.5 ± 1.2	51.5 ± 1.4 *
MCL#3	9.4 ± 0.5	23.8 ± 1.0	25.1 ± 1.7	64.9 ± 2.5**

NOTE: Primary MCL cells from three patients and normal CD34+ cells were treated in triplicate for 48 hrs with the indicated doses of PS and BZ. Following this, the average viability of cells was assessed using trypan blue dye exclusion and a hemocytometer

^*p ≤ 0.05,

^**p ≤ 0.005.

Values represent the percentage of dead cells ± standard deviation from each condition as compared with untreated cells.