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Kaplan-Meier recurrence-free survival curves based on promoter hypermethylation of tumor suppressor genes. Curves are shown for RIZ1: (A), tumorous tissues, (B) non-tumorous tissues; and p16: (C) tumorous tissues, (D) non-tumorous tissues. P-values from Log-Rank (Mantel-Cox) tests are shown for differences in time to recurrence according to methylation status.
