Table 3.
Two Most Strongly Associated SNPs from the Seoul Project for Log10(Total Adiponectin) Based on Linear Regression Model and Meta-analysis Results in 6,305 Samples
SNP |
Seoul |
Ansan |
Bundang-gu |
Meta-analysis Effect Size (μg/ml) | Meta-analysis p Value | Meta-analysis Heterogeneity Q (p) |
---|---|---|---|---|---|---|
Effect Size (SE) (μg/ml) | Effect Size (SE) (μg/ml) | Effect Size (SE) (μg/ml) | ||||
rs3865188 | −0.095 (0.0118) | −0.096 (0.0073) | −0.079 (0.0066) | −0.09 | 2.82 × 10−83 | 3.58 (0.167) |
rs12596316 | −0.088 (0.012) | −0.096 (0.0074) | −0.076 (0.0065) | −0.09 | 3.09 × 10−77 | 4.13 (0.1268) |
p values were calculated under a linear regression under an additive model incorporating age, sex, smoking status, and body mass index as covariates. Effect sizes are given with standard error (SE).