Table 2.
Participant characteristics in relation to glomerular filtration rate based on cystatin C (eGFRcys) or creatinine (eGFRcreat), ARIC, 1996–98
| Characteristic | eGFRcys (ml/min/1.73 m2) |
P-trend | ||
|---|---|---|---|---|
| ≥90 (n = 3088) | 60–89 (n = 6265) | 15–59 (n = 1347) | ||
| Age, years (SD) | 60.5 (5.1) | 63.2 (5.6) | 65.8 (5.4) | <0.0001 |
| Male, n (%) | 1451 (47.0) | 2732 (43.6) | 530 (39.4) | <0.0001 |
| African Americans, n (%) | 1198 (38.8) | 988 (15.8) | 197 (14.6) | <0.0001 |
| HRT use,an (%) | 567 (34.6) | 882 (25.0) | 155 (19.0) | <0.0001 |
| BMI, kg/m2 (SD) | 27.7 (4.9) | 28.9 (5.5) | 30.1 (6.3) | <0.0001 |
| Diabetes, n (%) | 566 (18.5) | 884 (14.2) | 293 (21.8) | 0.7 |
| Factor VIII,b % (SD) | 124 (36) | 127 (35) | 140 (41) | <0.0001 |
| aPTT,b seconds (SD) | 29.3 (2.9) | 29.1 (3.0) | 28.9 (3.1) | 0.0005 |
| eGFRcreat (ml/min/1.73 m2) | ||||
| Characteristic | ≥90 (n = 4273) | 60–89 (n = 5769) | 15–59 (n = 658) | P-trend |
| Age, years (SD) | 60.4 (5.2) | 64.0 (5.4) | 66.8 (5.2) | <0.0001 |
| Male, n (%) | 1812 (42.4) | 2607 (45.2) | 294 (44.7) | 0.01 |
| African Americans, n (%) | 1262 (29.5) | 971 (16.8) | 150 (22.8) | <0.0001 |
| HRT use,an (%) | 710 (28.9) | 823 (26.0) | 71 (19.5) | <0.0001 |
| BMI, kg/m2 (SD) | 29.0 (6.0) | 28.4 (5.1) | 29.3 (5.3) | 0.007 |
| Diabetes, n (%) | 777 (18.3) | 801 (13.9) | 165 (25.2) | 0.29 |
| Factor VIII,b % (SD) | 126 (35) | 128 (36) | 139 (42) | <0.0001 |
| aPTT,b seconds (SD) | 29.2 (3.1) | 29.1 (2.9) | 28.8 (2.9) | 0.004 |
a
Women only.
b
1987–89 value.